With up to 488 calories and up to 31.8 grams of protein per serving, we’re impressed by Crazy Nutrition’s Mass Gainer. These calorie-rich powders can help you maintain a calorie surplus for weight gain while also delivering key doses of macronutrients, most notably protein. If we’re talking mass and muscle, the best mass gainers can be prime selections for your daily routine. (7) You can take this supplement at just about any point before, after, or during your workout. Other BCAA supplements can typically cost below $1.25, with some even totaling below $0.50. (That said, if flavor variety is something you’re after, you’d likely be better served by BCAA supplements from Transparent Labs or Nutricost, both of which offer a larger selection of tastes.) No bloating, no weird aftertaste — just solid gains and a better workout experience." – Ellery Blackwood It’s like the creatine gave me an extra edge I didn’t know I needed. What surprised me most was how well my recovery improved — I was hitting new PRs without feeling wiped out. As palate-pleasing as this powder is, though, we do recommend paying close attention to your mixing procedure. After comparing this product to others, we gave the value a 5 out of 5 rating, given it’s approachable price point. You could also, of course, opt for a pre-workout, as the majority of formulations include beta-alanine. Testosterone can potentially boost skeletal musculature, which may help you on your journey to gain mass. HGH Activator works by encouraging the body to produce more HGH, which directly impacts muscle recovery, fat reduction, and overall muscle mass. Let’s take a look at some of the best muscle-building supplements that you should look out for in 2026. He explains that consuming protein after workouts stimulates muscle repair and recovery. Dr. Stefan M. Pasiakos, Director of the NIH Office of Dietary Supplements, highlights protein as the best supplement for muscle growth. P6 is formulated for men wanting supplement capsules for muscle growth that are both safe and effective, supporting strength, energy, and endurance for everyday performance and workout recovery. The most essential supplements for muscle building include protein powder, creatine, and branched-chain amino acids (BCAAs). Whether used post-workout or as a meal replacement, MusclePharm Combat Protein Powder supports fast muscle growth supplements and helps users build lean mass while promoting recovery and strength gains. But for most people, even though it’s a great supplement I’d recommend for overall health, for actual muscle growth benefits it’s going to have to land in C-Tier on our list of the best muscle mass building supplement. The best supplements for muscle growth and bodybuilding are protein and creatine. When you stop taking creatine, your creatine levels will gradually drop over the next few weeks. Creatine can also increase the amount of phosphocreatine in your brain, which may help with your memory. ATP is a source of energy that your cells use when you exercise. Phosphocreatine then helps create adenosine triphosphate (ATP). If you have bipolar disorder, creatine may also increase your risk of mania. As such, one of the best pre-workout supplements can be an excellent addition to your regimen if increased strength is your main goal. Tag along with Nick English as he breaks down our top picks for the best muscle-building supplements on the market in 2025. The key is in determining which are right for your goals, and which products best support the strength training regimen you’ll need for muscle growth. However, the number of supplements designed to help you earn that jacked physique goes well beyond the best protein powders. Whether you’re a bodybuilder or simply aiming to improve your muscle tone, this product helps maximize your results without resorting to synthetic substances. This supplement has made a real impact on my fitness progress, and I feel like I’m getting the most out of my workouts."-Ethan Lewis The substance boosts the amount of nitrogen retained in muscle tissue, which boosts protein synthesis. My lean muscle mass has increased significantly, which has really improved muscle definition.