The peptides and potassium of flaxseed reduce the risk of blood platelet aggregation, blood pressure, and free radicals in the blood and finally decrease the risk of cardiovascular disease. As a result of the beneficial effects of functional foods such as flaxseed in the prevention of diseases as well as their role in losing weight and decreasing body mass index (BMI) they have been studied frequently (71). In a case study, it was manifested that flaxseed consumption (30 g/day for 4 months) decreased testosterone and increased the insulin level in a 31-years old woman with PCOS (66). In a study on 14 healthy men, it was presented that diets of 50 to 60 g of fiber from mixed sources decrease prostate-specific antigen (PSA) (51). It has been shown that α-Linolenic acid has anti-inflammatory effects, and also antiproliferative activities were shown in premenopausal animal models of breast cancer. Bacteria in the gut transform the SDG of flax to the lignans-enterodiol and enterolactone which cause useful outcomes such as estrogenic or anti-estrogenic and anti-oxidant effects (11). Particularly, we focused on the mechanisms underlying flaxseed effects on hepatic, neurological, cardiovascular, gastrointestinal, reproductive, and urological disorders, and also its anti-oxidant, antidiabetic, and anticancer properties. Thus, the data from this case study are intriguing since results suggest that the reductions in androgen levels afforded by flaxseed supplementation are roughly 2–4 fold higher than those reported with other dietary interventions conducted previously. Moreover, a clinical trial illustrated the favorable effect of flaxseed on sex hormones, only in overweight and obese women (20). Although the lignan contents of flaxseed could regulate the sex hormones and consequently influence the incidence of related disease, the exact effect of flaxseed supplementation on sex hormones was not clear. We aimed to carry out a systematic review and meta-analysis of randomized controlled trials (RCTs) investigating effects of flaxseed supplementation on sex hormone profile. Inconsistent data suggest that flaxseed supplementation may have a role in sex hormones. Also, lowering your zinc and vitamin D intake will slow down your T-hormone production and decrease your testosterone levels. Fast food with high amounts of trans fats may not only reduce your testosterone levels, it may have other harmful effects. Consumption of flaxseed and any foods that destroy testosterone will decrease T levels in males . Two cinnamic acid connections constitute phenolic compounds called plant lignans. The nutritional value and amino acid profile of flaxseed and soya are comparable. Flaxseed oil is full of anti-oxidants such as tocopherols and betacarotene, nevertheless, common pure flaxseed oil oxidizes quickly after being exploited. Biological activities of flaxseed against different disorders based on experimental studies A type of flaxseed called solin has a different oil profile and ω-3 fatty acids numbers compared with others. Brown and yellow flaxseeds have equal numbers of short-chain ω-3 fatty acids and identical nutritional features. Therefore, the prevention and management of disharmony in sex hormones are very worthful. Estrogen and progesterone are the main female sex hormones that their production and secretion are triggered by pituitary hormones including follicle-stimulating hormone (FSH) and luteinizing hormone (LH) (1). Sex hormones and their harmony have been considered as an important issue, due to their interactions with body tissues. Flaxseed supplementation had no significant effect on sex hormones in adults. Potential side effects of fibremaxxing Healthy street foods to enjoy Gym to plate, post-workout eating risk